The University of Texas MD Anderson Cancer Center (UT MDA) is a world-renowned cancer research and treatment institution. It was founded in 1941 and is a member of the University of Texas system. Its clinical diagnosis and treatment of tumors and basic medical research enjoy a high reputation around the world. It has been rated as the best cancer research institution in the United States many times.

Texas Children's Hospital is one of the best children's hospitals in the United States. It was founded in 1954 and is located in Houston. It has 595 beds (USNEWS data) and is affiliated with Baylor College of Medicine. In the USNews 2014-15 ranking of the best children's hospitals in the United States, Texas Children's Hospital ranked 4th.

The Johns Hopkins Hospital is a large general hospital in the United States, built in 1889 and located in Baltimore, Maryland. Johns Hopkins Hospital has been named the best hospital in the United States by USNews for more than 20 consecutive years (ranked third in 2014-2015). The Johns Hopkins Hospital has had a profound impact on the development of medicine. It has performed the world's first complete sex reassignment surgery, the first neonatal tetralogy of Fallot surgery, the first heart bypass surgery, and the first isolation of poliomyelitis. Viruses, first used in surgical procedures rubber gloves. Kidney dialysis, cardiopulmonary resuscitation, etc. were first started at Johns Hopkins Hospital.

Massachusetts General Hospital (MGH) is one of the best hospitals in the United States. Founded in 1811, it is located in Boston and is the oldest hospital in New England. Massachusetts General Hospital has been rated as one of the best hospitals in the United States by U.S. News and World Report for many years in a row, ranking second in 2014-2015.

The University of California, Los Angeles Medical Center (UCLA Medical Center) is one of the best large general hospitals in the United States. It was established in 1955. In the U.S. News ranking of the best hospitals in the United States, UCLA has long been ranked among the top 5 in the United States. UCLA has very high standards in organ transplantation, geriatrics, urology, etc.

Cleveland Clinic is a large general hospital in the United States and one of the best hospitals in the United States. It was founded in 1921 and is located in Cleveland, Ohio. Since 1995, Cleveland Clinic has been ranked No. 1 in US News' cardiology rankings.

New York-Presbyterian University Hospital of Columbia and Cornell (NYP, New York-Presbyterian University Hospital of Columbia and Cornell) is one of the best hospitals in the United States. In 1998, it was established by New York Hospital (established in 1771, It was formed by the merger of Cornell University Medical School Hospital) and Presbyterian Hospital (founded in 1868 as Columbia University Medical School Hospital), becoming the largest hospital in New York State. In the 2015 USNews ranking of America's Best Hospitals, NewYork-Presbyterian Hospital ranked 6th.

Cincinnati Children's Hospital Medical Center is one of the best pediatric hospitals in the United States. It was founded in 1883 and has 539 beds (2014 data). Cincinnati Children's Hospital Medical Center ranked No. 3 in usnews' 2014-15 ranking of America's Best Children's Hospitals.

The Mayo Clinic (also known as the Mayo Clinic) is a world-renowned private non-profit comprehensive medical institution. It was founded by Dr. Mayo in Rochester, Minnesota in 1864. It is one of the best hospitals in the United States. In the 2014-2015 Usnews ranking of America's Best Hospitals, Mayo Clinic ranked first. The Mayo Clinic helped establish the medical school at the University of Minnesota and later established its own Mayo School of Medicine.